Skip navigation

Example media interest

  • July 2023: BBC "Stay Young" series with Michael Mosley, featuring interview with CamCAN participant and report of some CamCAN findings.
  • Dec 2020: BBC Radio 4 interview for All in the Mind about importance of mid-life activities for old-age cognition.
  • Jan 2020: Article in Mathworks newsletter about advantage of Matlab software for CamCAN imaging analysis.
  • Aug 2018: Article in Daily Mail about mid-life activities relating to late-life cognitive health.
  • May 2015: Articles in Science Daily and Health Imaging about individual differences in brain activity.
  • Dec 2014: Articles in Daily Mail and The Times about effect of age on executive functions.
  • Jun 2014: BBC interview on Radio 4 about CamCAN.
  • Sep 2012: Podcast by Naked Scientists about CamCAN.

BBSRC Cam-CAN Promotional Films

In July 2013 the BBSRC released 5 short promotional videos about the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), which can be found here:

More videos

Recent, example Cam-CAN Recorded Talks

Scientific Publications

For CamCAN members and affiliates with approved projects, please refer to this page for publication conditions; for non-CamCAN researchers with approved access via the data-sharing portal, please refer to this page for publication conditions.



In press


  • Lugtmeijer, S., Geerligs, L., Tsvetanov, K.A., Mitchell, D.J., Cam-CAN & Campbell, K.L. (2023). Lifespan differences in visual short-term memory load-modulated functional connectivity. Neuroimage, 270, 119982. [Cam-CAN Author list 14] DOI
  • King, D.L.O., Henson, R.N., Kievit, R., Wolpe, N., Brayne, C., Tyler, L.K., Rowe, J.B., Cam-CAN & Tsvetanov, K.A. (2023). Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities. Scientific Reports, 13:978. [Cam-CAN Author list 14] DOI
  • Mitchell, D., Mousley, A., Shafto, M., Cam-CAN, Duncan, J. (2023). Neural contributions to reduced fluid intelligence across the adult lifespan. Journal of Neuroscience [Cam-CAN Author list 14] DOI


  • Wu, S., Tyler, L.K., Henson, R.N., Rowe, J.B., Cam-CAN, Tsvetanov, K.A. (2022). Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the adult lifespan. Neurobiology of Aging, 121, 1-14 [Cam-CAN Author list 14] DOI
  • Liu, X., Tyler, L.K., Cam-CAN, Rowe, J.B., Tsvetanov, K.A. (2022). Multimodal fusion analysis of functional, cerebrovascular and structural neuroimaging in healthy aging subjects. Human Brain Mapping, 43, 5490-5508 [Cam-CAN Author list 14] DOI
  • Bethlehem et al. (2022). Brain charts for the human lifespan. Nature, 604, 7904. [Cam-CAN Author list 14] DOI
  • Tomassini, A., Hezemans, F.H., Ye, R., Tsvetanov, K.A., Wolpe, N. & Rowe, J.B. (2022). Prefrontal Cortical Connectivity Mediates Locus Coeruleus Noradrenergic Regulation of Inhibitory Control in Older Adults. Journal of Neuroscience, 42, 3484-3493. [Cam-CAN Author list 13] DOI
  • Stretton, J., Schweizer, S., Dalgleish, T. & Cam-CAN (2022). Age-related enhancements in positive emotionality across the lifespan: structural equation modelling of brain and behaviour. Journal of Neuroscience. [Cam-CAN Author list 13] DOI
  • Kocagoncu, E., Nesbitt, D., Emery, T., Hughers, L., Henson, R. & Rowe, J. (2022). Neurophysiological and brain structural markers of cognitive frailty differ from Alzheimer's disease. Journal of Neuroscience, 42, 1362–1373. [Cam-CAN Author list 13] PubMed
  • Tibon, R. & Tsvetanov, K.A. (2022). The “Neural Shift” of Sleep Quality and Cognitive Aging: A Resting-State MEG Study of Transient Neural Dynamics. Frontiers in Aging Neuroscience, [Cam-CAN Author list 13] PubMed


  • Knights, E., Morcom, A., Cam-CAN & Henson, R. (2021) Does Hemispheric Asymmetry Reduction in Older Adults (HAROLD) in motor cortex reflect compensation? Journal of Neuroscience, 41, 9361–9373. [Cam-CAN Author list 13] PubMed
  • Tibon, R., Tsevtanov, K.A., Price, D., Nesbitt, D., Cam-CAN & Henson, R.N. (2021). Transient neural network dynamics in cognitive ageing. Neurobiology of Aging, 105, 217-228. [Cam-CAN Author list 13] PubMed


  • Tsvetanov, K.A., Henson, R.N.A., Jones, S., Mutsaerts, H-J., Fuhrmann, D., Tyler, L.K., Cam-CAN, & Rowe, J.B. (2020). The effects of age on resting-state BOLD signal variability is explained by cardiovascular and neurovascular factors. Psychophysiology, 13714. [Cam-CAN Author list 13] Open Access
  • Liu, K.Y, Kievit, R.A., Tsvetanov, K.A., Betts, M.J., Duzel, E., Rowe, J.B. Cam-CAN, Howard, R. & Hammerer, D. (2020). Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences. Nature Communications, 1712. [Cam-CAN Author list 13] Open Access
  • Bethlehem, R., Paquola, C., Seidlitz, J., Ronan, L., Bernhard, B., Cam-CAN & Tsvetanov, K.A. (2020). Dispersion of functional gradients across the adult lifespan. Neuroimage, 117299. [Cam-CAN Author list 13] Open Access
  • Lehmann, B.C.L., Henson, R.N., Geerligs, L., Cam-CAN & White, S.R. (2020). Characterising group-level brain connectivity: A framework using Bayesian exponential random graph models. Neuroimage, 117480. [Cam-CAN Author list 13] Open Access
  • Henson, R.N., Suri, S., Knights, E., Rowe, J.B., Kievit, R.A., Lyall, D.M., Chan, D., Eising, E. & Fisher, S.E. (2020). Effect of APOE polymorphism on cognition and brain in the CamCAN cohort. Brain and Neuroscience Advances, 4, 1-12. [Cam-CAN Author list 13]. Stage 2 Registered Report.
  • Borgeest, G., Henson, R., Shafto, M., Samu, D., Cam-CAN, Kievit, R. (2020). Greater lifestyle engagement is associated with healthy cognitive ageing. PLOS ONE, 15, e0230077. [Cam-CAN Author list 12]
  • Strommer, J.M., Davis, S.W., Henson, R.N., Tyler, L.K., Cam-CAN & Campbell K.L. Physical activity predicts population-level age-related differences in frontal white matter (2020). The Journals of Gerontology: Biological Sciences, 2, 236–243. [Cam-CAN Author list 12] Open Access.
  • Wolpe, N., Ingram, J.N., Tsvetanov, K.A, Henson, R.N, Wolpert, D.M., Cam-CAN, Rowe, J. (2020). Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory. Neurobiology of Aging, 90, 13-23 [Cam-CAN Author list 13]


  • Shafto MA, Henson RN, Matthews FE, Taylor JR, Emery T, Erzinclioglu S, Hanley C, Rowe JB, Cusack R, Calder AJ, Marslen-Wilson WD, Duncan J, Dalgleish T, Brayne C, Cam-CAN, Tyler LK. (2019). Cognitive Diversity in a Healthy Aging Cohort: Cross-Domain Cognition in the Cam-CAN Project. J Aging Health. [Cam-CAN Author list 12] Open Access.
  • Schweizer, S., Stretton, J., Van Belle, J., Price, D., Calder, A.J., Cam-CAN and Dalgleish, T. (2019). Age-related decline in emotional positivity and emotion regulation in a population-derived cohort. Social Cognitive and Affective Neuroscience, 623-631 [Cam-CAN Author list 12] Open Access.
  • Bruffaerts, R., Tyler, L.K., Shafto, M., Tsvetanov, K.A., Cam-CAN and Clarke, A. (2019). Perceptual and conceptual processing of visual objects across the adult lifespan. Scientific Reports, 9:13771. [Cam-CAN Author list 12] Open Access.
  • Fuhrmann, D., Nesbitt, D., Shafto, M., Rowe, J.B., Price, D., Gadie, A., Cam-CAN, Kievit, R.A. (2019). Cardiovascular risk factors for micro- and macro-structural brain changes in healthy ageing. Neurobiology of Aging, 74, 46-55. [Cam-CAN Author list 12] Open Access.
  • Liu, K.Y., Acosta-Cabronero, J., Cardenas-Blanco, A., Loane, C., Berry, A,J,, Betts, M.J., Kievit, R.A., Henson, R.N., Duzel, E., Cam-CAN, Howard, R., Hammerer, D. (2019). In vivo visualization of age-related differences in the locus coeruleus. Neurobiology of Aging, 74, 101-111. [Cam-CAN Author list 12] Open Access.
  • Bardouille, T., Bailey, L. Cam-CAN. Evidence for age-related changes in sensorimotor neuromagnetic responses during cued button pressing in a large open-access dataset (2019). Neuroimage, 193, 25-34. [Cam-CAN Author list 12] Open Access


  • Chan, D., Shafto, M., Kievit, R., Matthews, F., Spink, M., Valenzuela, M., Cam-CAN and Henson, R.N. (2018). Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation and late-life activities. Neurobiology of Aging, 70, 180-183. [Cam-CAN Author list 12] Open Access.
  • de Mooij, S. M. M., Henson, R. N., Waldorp, L. J., Kievit, R. A.. (2018). Age differentiation within grey matter, white matter and between memory and white matter in an adult lifespan cohort. Journal of Neuroscience, 38, 5826-5836. [Cam-CAN Author list 12] Open Access.
  • Morcom, A. CamCAN, Henson, R. N. (2018). Increased prefrontal activity with aging reflects nonspecific neural responses rather than compensation. Journal of Neuroscience, 1701-1717. [Cam-CAN Author list 12] Open Access
  • Tsvetanov, K., Ye, Z., Samu, D., Treder, M.S., Wolpe, N., Tyler, L.K., Rowe, J.R., CamCAN (2018). Activity and connectivity differences underlying inhibitory control across the adult lifespan. Journal of Neuroscience, 38, 7887-7900. [Cam-CAN Author list 12] Open Access
  • Green, E., Bennett, H., Brayne, C., Cam-CAN, Matthews, F.E. (2018). Exploring patterns of response across the lifespan: the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study. BMC Public Health, 18:760. [Cam-CAN Author list 12] Open Access.
  • Wolpe N, Zhang J, Nombela C, Ingram JN, Wolpert DM, Cam-CAN, Rowe JB (2018). Sensory attenuation in Parkinson's disease is related to disease severity and dopamine dose. Scientific Reports, 8, 15643 [Cam-CAN Author list 12] Open Access.
  • Geerligs, L, Cam-CAM, Campbell, K. L. (2018). Age-related differences in information processing during movie watching. Neurobiology of Aging, 72, 106-120. [Cam-CAN Author list 12] Open Access.
  • Liu, K.Y., Acosta-Cabronero, J., Cardenas-Blanco, A., Loane, C Berry, A.J., Betts, M.J., Kievit, R.A., Henson, R.N., Duzel, E., Cam-CAN, Howard, R.,Hammerer, D. (2018). In vivo visualization of age-related change in the locus coeruleus. Neurobiology of Aging, 17, 101-111. [Cam-CAN Author list 12] Open Access.
  • Mitchell, D. J., Cam-CAN, and Cusack, R. (2018). Visual short-term memory through the lifespan: Preserved benefits of context and metacognition. Psychology and Aging, 33(5), 841-854. [Cam-CAN Author list 12] Open Access.


  • Lehmann, B., White, S., Henson, R., Cam-CAN, Geerligs, L. (2017). Assessing dynamic functional connectivity in heterogeneous samples. NeuroImage. 157, 635-647. [Cam-CAN Author list 12] Open Access
  • Schweizer, S., Kievit, R. A., Emery, T., Cam-CAN, and Henson, R. N. (2017). Symptoms of Depression in a Large Healthy Population Cohort are related to Subjective Memory Complaints and Memory Performance in Negative Contexts. Psychological Medicine. 1-11. doi:10.1101/101642 [Cam-CAN Author list 12] Open Access
  • Geerligs, L., Tsvetanov, K., Cam-CAN and Henson, R.N. (2017). Challenges in measuring individual differences in functional connectivity using fMRI: the case of healthy aging. Human Brain Mapping. 38, 4125-4165. [Cam-CAN Author list 12] Open Access
  • Price, D., Tyler, L. K., Neto Henriques, R., Campbell, K. R., Williams, N., Treder, M., Taylor, J., Cam-CAN, Henson, R. (2017). Age-Related Delay in Visual and Auditory Evoked Responses is Mediated by White- and Gray-matter Differences. Nature Communications 8, 15671. [Cam-CAN Author list 12] PDF.
  • Samu, D., Campbell, K., Tsvetanov, K., Shafto, M., Cam-CAN, and Tyler, L. K. (2017). Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity. Nature Communications. 8, 14743. [Cam-CAN Author list 12] Open Access
  • Gadie, A., Shafto, M., Leng, Y., Cam-CAN, Kievit, R. A. (2017). Age-related differences in self-reported sleep quality predict healthy ageing across multiple domains: a multi-modal cohort of 2406 adults. BMJ Open. 7(7). Open Access [Cam-CAN Author list 12].
  • Taylor, J.R., Williams, N., Cusack, R., Auer, T., Shafto, M.A., Dixon, M., Tyler, L.K., Cam-CAN, Henson, R.N. (2017). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) data repository: Structural and functional MRI, MEG, and cognitive data from a cross-sectional adult lifespan sample. NeuroImage. 144, 262-269. doi: 10.1016/j.neuroimage.2015.09.018. [Cam-CAN Author list 12]. PDF


  • Wolpe, N., Ingram, J., Tsvetanov, K., Geerligs, L., Kievit, R., Henson, R., Wolpert, D., Cam-CAN & Rowe, J. (2016). Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits. Nature Communications, 7. [Cam-CAN Author list 12] Open Access
  • Kievit, R. A., Davis, S. W., Griffiths, J., Correia, M., Cam-CAN, Henson, R. N. A. (2016). A watershed model of individual differences in fluid intelligence. Neurophychologia. [Cam-CAN Author list 12] PDF
  • Henson, R.N., Campbell, K.L., Davis, S.W., Taylor, J.R., Emery, T., Erzinclioglu, S., Cam-CAN & Kievit, R.A. (2016). Multiple determinants of lifespan memory differences. Scientific Reports, 6(32527) [Cam-CAN Author list 12] PDF
  • Blenkmann, A., Hughes, L. E., Kochen, S., Bekinschtein, T. A., Cam-CAN, Rowe, J. B. (2016). Convergent evidence for hierarchical prediction networks from human electrocorticography and magnetoencephalography. Cortex. 82, pp. 192-205. [Cam-CAN Author list 12] PDF
  • Ronan, L., Alexander-Bloch, A. F., Wagstyl, K., Farooqi, S., Brayne, C., Tyler, L. K., Cam-CAN, Fletcher, P. C. (2016). Obesity associated with increased brain-age from mid-life. Neurobiology of Ageing. [Cam-CAN Author list 12] PDF
  • Geerligs, L., Cam-CAN & Henson, R.N. (2016). Functional connectivity and structural covariance between regions of interest can be measured more accurately using multivariate distance correlation. Neuroimage, 135, 16-31. [Cam-CAN Author list 12] PDF
  • Shafto, M. A., James, L. E., Abrams, L., Cam-CAN. Tyler, L. K. (2017). Age-Related Increases in Verbal Knowledge Are Not Associated With Word Finding Problems in the Cam-CAN Cohort: What You Know Won't Hurt You. Journals of Gerontology B: Psychological Sciences. 72(1), 100-106. DOI: 10.1093/geronb/gbw074. [Cam-CAN Author list 12]. PDF
  • Campbell, K. L., Samu, S., Davis, S. W., Geerligs, L., Mustafa, A., Cam-CAN, Tyler, L. K. (2016). Robust Resilience of the Frontotemporal Syntax System to Aging. Journal of Neuroscience. 36(19): 5214-5227; doi: 10.1523/JNEUROSCI.4561-15.2016. [Cam-CAN Author list 12]. PDF
  • Tsvetanov, K. A., Henson, R. N. A., Tyler, L. K., Razi, A., Geerligs, L., Ham, T., CamCAN, Rowe, J. (2016). Extrinsic and intrinsic brain network connectivity maintains cognition across the lifespan despite accelerated decay of regional brain activation. The Journal of Neuroscience. 36(11), 3115-3126. [Cam-CAN Author list 12]. PDF


  • Green, E., Shafto, M. A., Matthews, F. E., Cam-CAN., White, S. R. (2015). Adult Lifespan Cognitive Variability in the Cross-Sectional Cam-CAN Cohort. International Journal of Environmental Research and Public Health. 2015, 12(12), 15516-15530. doi: 10.3390/ijerph121215003. [Cam-CAN Author list 12]. PDF
  • Campbell, K. L., Shafto, M.A., Wright, P., Tsvetanov, K.A., Geerligs, L., Cusack, R., Cam-CAN, & Tyler, L.K. (2015). Idiosyncratic responding during movie-watching predicted by age differences in attentional control. Neurobiology of Aging. doi: 10.1016/j.neurobiolaging.2015.07.028 [Cam-CAN Author list 11]. PDF
  • Geerligs, L., Rubinov, M., Cam-CAN, & Henson, R.N. (2015). State and trait components of functional connectivity: individual differences vary with mental state. Journal of Neuroscience, 35(41), 13949 –13961. doi:10.1523/jneurosci.1324-15.2015 [Cam-CAN Author list 11]. PDF
  • Tsvetanov, K.A., Henson, R.N.A., Tyler, L.K., Davis, S.W., Shafto, M., Taylor, J.R., Williams, N., Cam-CAN, & Rowe, J.B. (2015). The effect of ageing on fMRI: correction for the confounding effects of vascular reactivity evaluated by joint fMRI and MEG in 335 adults. Human Brain Mapping, 36(6), 2248-2269. doi: 10.1002/hbm.22768 [Cam-CAN Author list 11]. PDF


  • Shafto, M.A., Tyler, L.K. (2014). Language in the aging brain: The network dynamics of cognitive decline and preservation. Science, 346(6209), pp. 583-587. DOI: 10.1126/science.1254404. PDF
  • Kievit, R.A., Davis, S.W., Mitchell, D.J., Taylor, J.R., Duncan, J., Cam-CAN, & Henson, R.N.A. (2014). Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking. Nature Communications, 5, 5658. DOI: 10.1038/ncomms6658. [Cam-CAN Author list 7]. PDF
  • Shafto, M.A., Tyler, L.K., Dixon, M., Taylor, J.R., Rowe, J.B., Cusack, R., Calder, A.J., Marslen-Wilson, W.D., Duncan, J., Dalgleish, T., Henson, R.N., Brayne, C., Cam-CAN, & Matthews, F.E. (2014). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing. BMC Neurology, 14(204). doi:10.1186/s12883-014-0204-1. [Cam-CAN Author list 10]. PDF

Selection of Non-CamCAN Publications Using CamCAN Data

Note: not complete; for full list, see PubMed Citations

  • Denis A Engemann Is a corresponding author, Oleh Kozynets, David Sabbagh, Guillaume Lemaitre, Gael Varoquaux, Franziskus Liem, Alexandre Gramfort (2020). Combining magnetoencephalography with magnetic resonance imaging enhances learning of surrogate-biomarkers. Elife. OpenAccess
  • Kathryn L. West, Mark D. Zuppichini, Monroe P. Turner, Dinesh K. Sivakolundu, Yuguang Zhao, Dema Abdelkarim, Jeffrey S. Spence & Bart Rypma (2019). BOLD hemodynamic response function changes significantly with healthy aging. Neuroimage. OpenAccess
  • Ben-Yakov, A. & Henson, R.N. (2018). The hippocampal film-editor: sensitivity and specificity to event boundaries in continuous experience. Journal of Neuroscience, 38, 10057-10063. OpenAccess
  • Gaelle Doucet, Dominik A. Moser, Amanda Rodrigue, Danielle Bassett, David Glahn & Sophia Frangou (2017). Person-Based Brain Morphometric Similarity is Heritable and Correlates With Biological Features. Cerebral Cortex Open Access
  • Kljajevic, V. and Erramuzpe, A. (2018). Proper name retrieval and structural integrity of cerebral cortex in midlife: A cross-sectional study. Brain and Cognition, 120, 26-33. PubMed
  • Kuhn T, Kaufmann T, Doan NT, Westlye LT, Jones J, Nunez RA, Bookheimer SY, Singer EJ, Hinkin CH, Thames AD. (2018) An augmented aging process in brain white matter in HIV. Human Brain Mapping, 39, 2532-2540. PubMed
  • Lancaster J, Lorenz R, Leech R, Cole JH. (2018) Bayesian Optimization for Neuroimaging Pre-processing in Brain Age Classification and Prediction. Front Aging Neurosci, 12;10:28 PubMed
  • Madan CR. (2018) Advances in Studying Brain Morphology: The Benefits of Open-Access Data. Front Hum Neurosci. 4;11:405 PubMed
  • Don Krieger, Paul Shepard, Ben Zusman, Anirban Jana, David O. Okonkwo. (2017). Shared High Value Research Resources: The CamCAN Human Lifespan Neuroimaging Dataset Processed on the Open Science Grid. Proceedings of the 2017 IEEE International Conference on Bioinformatics and Biomedicine. ARxiv
  • Misquitta, K. et al. (2017) The relationship between brain atrophy and cognitive-behavioral symptoms in retired Canadian football players with multiple concussions. PubMed

Cam-CAN Corporate Author membership

The Cam-CAN project involves many different researcher and support staff whose efforts are acknowledged in publications and presentations under the Cam-CAN corporate authorship. A record of the Cam-CAN corporate author members appropriate for each output can be accessed by clicking on the 'Cam-CAN Author list x' links above.